Product Range

SIL-HT

Sample Injection Systems

SIL-HT
High throughput is the key word for modern HPLC analysis. The SIL-HT is excellent performing in terms of sample injection speed, sample capacity, and minimizing sample carryover of highly adsorbent sample components. These features are in increasingly high demand and essential for high throughput analysis. The SIL-HT has been developed to meet such users' requirements and will also provide optimum results in your lab. The SIL-HT is available in two versions: the SIL-HTA, ambient model; and the SIL-HTC with sample temperature control from 4 to 40C. The SIL-HT maximizes analysis throughput with fast sample injection and high sample capacity. Injection speed is 15 seconds for injecting samples of 10 µL . The SIL-HT is the one of fastest autosamplers currently on the market.

Recently, an increasing number of extremely basic and hydrophobic components are being used in new drug formulations. Since these chemical compounds strongly adsorb to the sampling needles or rotor seals (mainly Vespel) of autosamplers, cross contamination may not be reduced by simple rinsing. To minimize adsorption of such compounds, the outer surface of the sampling needle of the SIL-HT's autosampler is coated using a special, innovative surface processing technology (patent pending). Furthermore, by employing newly developed rotor seals and needle seals made of PEEK, the SIL-HT dramatically reduces contamination, even with the most highly adsorbent sample compounds. As a result, the SIL-HT demonstrates nearly zero sample carryover.

The SIL-HT uses a needle-in-the-flow-path injection design (also called direct injection method or total volume injection method) and a high-performance measuring pump (6 nL step resolution) for enhanced accuracy. This results in superior repeatability over conventional autosamplers. In addition, precious samples are not wasted since the total volume aspirated is injected. Depend on the sample trays the capacity is up to 100 4 ml vials or up to 4 microtiterplates (96 or 384 well) .

SIL-10AF / AP
These autosamplers based on the SIL-10A autosampler and are replace this model with different types dedicated to special applications: SIL-10AF for faster injection with injection volume up to 50 µl (standard loop, 2 ml with optional sample loop ) and SIL-10AP for analytical up to preparative injection volumes (up to 5 ml) . Both instruments are based on the loop injection principle

The time to sample injection is only 40 seconds (when injecting 10 µL). Even when the cleaning of the flow line after injection is included, 1 process will be finished in about 2 minutes. As a result, high throughput repeat analysis is possible, and sample preparations such as dilution and mixing can be performed rapidly. As well as being a multi-purpose autosampler, it is also capable of high speed sample injection. In particular, the time expended over time consuming sample preparation can be shortened substantially.

Furthermore, sample processing capability is enhanced greatly since two 96-well MTP (Microtiter plate) / DWP (Deep-well plate) plates can be used.

For control of the SIL-10AF/AP a System Controller SCL-10AVP or CBM-20A is necessary

 

SIL-HT