MALDI-Based Instruments and Solutions

MALDI-TOF (Matrix-Assisted Laser Desorption/Ionisation Time-of-Flight) Mass Spectrometry measures the mass of molecules from a matrix-embedded sample using a laser for minimal fragmentation. It's crucial for identifying and characterising high molecular weight compounds (proteins, peptides and synthetic polymers), and for microbial ID or food fraud detection. This technique also extends to MALDI Imaging Mass Spectrometry, providing the spatial distribution of molecules.

Shimadzu offers a vast portfolio of MALDI-based instruments and solutions. Our MALDI mass spectrometers include the compact MALDImini-1 and the high-performing MALDI-8020/30 benchtop linear MALDI-TOF. The AXIMA series MALDI spectrometers (TOF and TOF/TOF) provide simple, accurate mass measurements and are excellent for MALDI Mass Spectrometry Imaging.

At the forefront of innovation is the iMScope QT, which uniquely integrates high-resolution MALDI Imaging Mass Spectrometry with optical microscopy. This powerful combination enables precise molecular imaging and spatial localisation, offering new insights in pharmaceutical research, pathology, and life sciences.

Shimadzu’s high resolution mass spectrometry equipment is affordable and robust. Making it ideal for routine manual or automated analysis of diverse sample classes.