Preparative HPLC Systems

Preparative chromatography is essential for separating and refining high-purity target compounds from synthesis reactions or natural extracts. While traditional preparative HPLC systems are widely used, a Supercritical Fluid Chromatography (SFC), which utilises carbon dioxide as the mobile phase, offers several advantages. These include faster analysis times, up to 70% reduction in organic solvent usage, no need for fraction evaporation, and enhanced separation of isomers.

Both preparative HPLC and SFC systems are engineered to separate and collect large quantities of purified compounds efficiently, enabling further evaluation and downstream processing.

Shimadzu is a world-leading manufacturer of high-quality preparative HPLC systems that meet diverse application requirements. Our portfolio includes the Nexera Prep (HPLC preparative system), the Nexera UC Prep (SFC preparative system), and the UFPLC (Ultra-Fast Preparative and Purification Liquid Chromatography System), a fully automated solution from preparation to recovery.